L – Methyl Tetrahydrofolate Calcium (LMF) USP
L-Methyltetrahydrofolate Calcium (LMF) is the active, readily usable form of Vitamin B9 (folate) that supplements dietary folate, crucial for DNA/RNA synthesis, cell division, and red blood cell formation, often used for deficiencies, pregnancy, anemia, and to support mental health by helping with neurotransmitter production, especially beneficial for those with MTHFR gene variations who struggle with folic acid conversion
Uses: It is used to manage and treat:
Folate deficiency and certain types of anemia.
Hyperhomocysteinemia (high homocysteine levels), reducing the risk of cardiovascular disease.
Neural tube defects during pregnancy (essential for healthy fetal brain and spinal cord development).
As an adjunctive therapy to enhance the effect of antidepressant medications in major depressive disorder.
Peripheral neuropathy (nerve damage), often in combination with other B vitamins like methylcobalamin and pyridoxal-5-phosphate
Administration: It is typically an orally administered prescription dietary supplement taken daily, with or without food, as directed by a healthcare provider.
Side Effects: Most side effects are minor and temporary, but may include nausea, stomach upset, confusion, sleep disturbances, and irritability. Allergic reactions are rare.




