Alfuzosin ip/bp/usp

CAS number  81403-80-7

Chemical Formula  C19H27N5O4

For the reduction of urinary obstruction and relief of associated manifestations  in patients with symptomatic beningn prostatic hyperplasia.
Alfuzosin is a non-subtype specific alpha(1)-adrenergic blocking agent that exhibits selectivity for alpha(1)-adrenergic receptors in the lower urinary tract. Inhibition of these adrenoreceptors leads to the relaxation of smooth muscle in the bladder neck and prostate, resulting in the improvement in urine flow and a reduction in symptoms in benign prostate hyperplasia. Alfuzosin also inhibits the vasoconstrictor effect of circulating and locally released catecholamines (epinephrine and norepinephrine), resulting in peripheral vasodilation.