Tocopherol Polyethylene glycol succinate – CAS No 9002-96-4

Tocopherol polyethylene glycol succinate (TPGS), also known as tocofersolan or vitamin E-TPGS, is a water-soluble derivative of vitamin E (α-tocopherol). It’s a synthetic amphipathic compound that combines the antioxidant properties of vitamin E with the water solubility provided by polyethylene glycol (PEG).

Uses:
Drug Delivery: TPGS is used as a solubilizer, absorption enhancer, and permeation enhancer in drug delivery systems, particularly for poorly soluble drugs. It can improve the oral bioavailability of drugs and enhance their penetration into cells, according to a review on ScienceDirect.
Pharmaceutical Formulations: TPGS is used in various pharmaceutical formulations to enhance drug absorption, solubility, and stability,